Pharmaceutical manufacturing is driven by one of two vastly different strategies: reducing costs or incorporating new technologies, such as Process Analytical Technology (PAT) or new drug delivery vehicles. Reducing costs can result in utilizing unfamiliar raw material suppliers, which can result in unplanned process variability or process changes. Perhaps you are on the other side of this relationship, whereby you are unsure if your process changes will affect your customer.
On the other hand, newer materials and manufacturing techniques demand a better understanding of the process as a whole. This may include implementing various programs such as six sigma, PAT, quality by design, or specific FDA guidance documents, with the goal of improved quality and reduced time-to-market. Novel techniques can pose increased risk and effort to implement.
Jenike & Johanson can provide you with knowledge of how powders will behave from raw material dispensing, blending, storage, transfer, and through the creation of the final dose. This knowledge can be used to avoid and solve problems related to erratic or no-flow conditions (related to ratholing and/or arching), as well as segregation, blend and content uniformity.
Review our new service regarding analyzing production rate limitations
| Partial Client List |
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- Abbott Laboratories
- Agouron
- American Pharmaceutical Partners
- Amgen
- Aventis
- Bayer
- Bristol Myers Squibb
- Ciba Geigy
- Delsys Pharmaceutical
- Eli Lilly
- Genzyme
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- Inhale
- Janssen Pharmaceutical
- Johnson & Johnson
- JRH Biosciences
- Lederle Labs
- Merck
- Merck, Sharp & Dohme
- Novartis
- Ortho-McNeil Pharmaceutical
- Pfizer
- Pharmacia
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- Procter & Gamble
- Purepac Pharmaceuticals
- Rhone-Poulenc
- Roche
- SmithKline Beecham
- Syntex
- Warner Lambert
- Whitehall Labs
- Wyeth Ayerst
- Zeneca
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| Some of the Materials We Have Handled |
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- Analgesics
- ACE Inhibitors
- Antibiotics / Penicillin
- Anticoagulants
- Anticonvulsants
- Anti-depressants
- Antidiabetics
- Antihistamines
- Anti-impotence
- Channel Blockers
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- Cholinergics
- Cough / Cold / Allergy
- Hormones
- Narcotics
- NSAIDS
- Placebos
- Protease Inhibitors
- Reductase Inhibitors
- Vitamins
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- Powder Types
- Excipients
- Fine Granulations
- Low Dose, High Potency Direct Compression Blends
- Oral Suspensions
- Pure Active
- Wet and Dry Granulations
- Wide Particle Size Distribution Blends
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KEY ENGINEERING SERVICES
If your plant is currently experiencing solids handling, segregation, or conveying difficulties or implementing a new production line, contact Jenike & Johanson to help you prevent and solve food handling problems.
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